Lord Dowding Fund for humane research

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National Antivisection Society

New Science: issue 1

15 February 2008

1

New Science

A new magazine exploring the latest developments in the world of research without animals. Also featuring reports on the research we are funding.

If you are living in the UK or US and would like a free copy email your name and address today.

Microdosing: Fast forward

Introduction to the revolutionary, ultra sensitive test method, that could accelerate the development of new drugs and end the use of animals in tests…
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Mind’s Eye: The future of Neuroscience

Research we are supporting utilises cutting edge neuroimaging technology allowing static and real time brain imaging, including an LDF-sponsored Magnetic Resonance Imaging (MRI) scanner.
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MEG and auditory processing

The potential for helping people with hearing impairments and language disorders was studied using MEG to look at auditory processing. Animal model auditory research has historically focused on single-unit responses to stimuli, not the interaction of neurones. As a result of the lack of clarity which is produced by invasive measurements it will now be a challenge to understand how the non-invasive measures relate to them.
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A tissue construct model for investigating the therapeutic effects of ultrasound on cartilage

Clinical trials show that intensity pulsed ultrasound accelerates the healing of bone fractures by 30-40%. A new Lord Dowding Fund grant to researchers at the Eastman Dental Institute in London aims to result in a novel biological model of cartilage, free from animal-derived products, which can provide high quality tissue regeneration data for the establishment of clinical trial protocols. This could prevent animal suffering and benefit over 2million people in the UK alone.
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New approaches to neuro-toxicity testing

Two research projects by teams led by Dr Michael Coleman at Aston University with LDF support, have studied new approaches to testing for human neuro toxins.
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Extending the lifespan of computer–based alternatives

A new project is making our computer-assisted science teaching programmes globally accessible through the Internet, enabling multi-language versions to be created more easily than was previously possible. It will give life science and pharmacology teachers editorial control over the content of the programmes.
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A dynamic multi-cell type culture system as a model for Multiple Organ Dysfunction Syndrome (MODS)

A frequent consequence of sepsis is a syndrome known as MODS – Multiple Organ Dysfunction Syndrome – which results in the impermeable epithelial layers around the organs in the body (kidney, lungs, liver and intestines) becoming permeable, or “leaky”, causing organs to fail. A Lord Dowding Fund project aims to a cellular replacement for animal tests currently used.
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